Publications

Independent publications
196 Catalytic Asymmetric Synthesis of Cyclohexanes by Hydrogen Borrowing Annulations. Roly J. Armstrong, Wasim M. Akhtar, Tom A. Young, Fernanda Duarte and Timothy J. Donohoe, Angewandte Chemie Int. Ed., 2019, in the press. DOI: https://doi.org/10.1002/anie.201907514
Stacks Image 529
195 Rhodium-catalysed vinyl 1,4-conjugate addition coupled with Sharpless asymmetric dihydroxylation in the synthesis of the CDE ring fragment of pectenotoxin 4. Melodie Richardson, Darren Poole, Christopher Tame, Timothy J. Donohoe, Chem. Sci., 2019, 10, 6336-6340. DOI: 10.1039/C9SC01761E
Stacks Image 521
194 HFIP solvent enables alcohols to act as alkylating agents in stereoselective heterocyclisation. Yuxiang Zhu, Ignacio Colomer, Timothy J. Donohoe, J. Am. Chem. Soc., 2019, 141, 6489-6493. DOI: https://doi.org/10.1021/jacs.9b02198
Stacks Image 523
193 Synthesis of Lamellarin Alkaloids Using Orthoester-Masked α-Keto Acids. Harry J. Shirley, Maria Koyioni, Filip Muncan, Timothy J. Donohoe, Chem. Sci., 2019, 10, 4334 - 4338. DOI: 10.1039/C8SC05678A
Stacks Image 505
192 The reductive C3 functionalization of pyridinium and quinolinium salts through iridium-catalysed interrupted transfer hydrogenation. Alexandru Grozavu, Hamish B. Hepburn, Philip J. Smith, Harish K. Potukuchi, Peter J. Lindsay-Scott, Timothy J. Donohoe. Nature Chemistry, 2019, 11, 242-247. DOI: https://doi.org/10.1038/s41557-018-0178-5
Stacks Image 511
191 Stereoselective synthesis of cyclohexanes via an iridium catalysed (5+1) annulation strategy. Wasim M. Akhtar, Roly J. Armstrong, James R. Frost, N. G. Stevenson, Timothy J. Donohoe. J. Am. Chem. Soc., 2018, 140, 11916-11920. DOI: 10.1021/jacs.8b07776
Stacks Image 497
190 OBO-protected pyruvates as reagents for the synthesis of functionalized heteroaromatic compounds. C. Henrique Alves Estavez, Maria Koyioni, Kirsten E. Christensen, Peter D. Smith, Timothy J. Donohoe, Organic Letters, 2018, 20, 4048-4051. DOI: 10.1021/acs.orglett.8b01614
Stacks Image 489
189 Asymmetric Total Synthesis of (-)-(3R)-Inthomycin C. Sandra Balcells, Maxwell B. Haughey, Johannes C. L. Walker, Laia Josa-Cullere, Christopher Towers, Timothy J. Donohoe, Organic Letters, 2018, 20, 3583-3586. DOI: 10.1021/acs.orglett.8b01370
Stacks Image 493
188 The efficacy of the quercetin analogue LY294002 in immortalized cancer cell lines is related to the oxygenic and metabolic status of cells. Xinyue Huang, Michelle Potter, Ben Pilgrim, Ruchuta Ardkhean, Mikail Kabeshov, Timothy Claridge, Matthew Wiseman, Karl Jonathan Morten, Timothy Donohoe, Helen Elizabeth Townley. Int. J. Cancer Ther. Oncol., 2017, 5, 51X. DOI: 10.14319/ijcto.51.14
187 Cobalt versus osmium: control of both trans and cis selectivity in construction of the EFG rings of pectenotoxin 4. Ahria Roushanbakhti, Yifan Liu, Paul C. M. Winship, Michael J. Tucker, Wasim M. Akhtar, Daryl S. Walter, Gail Wrigley and Timothy J. Donohoe. Angewandte Chemie Int. Ed., 2017, 56, 14883-14887. DOI: 10.1002/anie.201708278
Stacks Image 481
186 Hexafluoroisopropanol as a highly versatile solvent. Ignacio Colomer, Anna E. R. Chamberlain, Maxwell B. Haughey and Timothy J. Donohoe. Nature Reviews Chemistry, 2017, 1, 0088. DOI: 10.1038/s41570-017-0088
Stacks Image 479
185 Pyruvate Enolate Arylation and Alkylation: OBO Ester Protected Pyruvates as Useful Reagents in Organic Synthesis. Carlos Henrique Esteves, Christopher J. J. Hall, Peter Smith and Timothy J. Donohoe. Organic Letters, 2017, 19, 5248-5251. DOI: 10.1021/acs.orglett.7b02524
Stacks Image 477
184 Catalytic enolate arylation with 3-bromoindoles allows the formation of beta-carbolines. C. Henrique Estavez Alves, Peter D. Smith, and Timothy J. Donohoe. J. Org. Chem. 2017, 82, 4435-4443. DOI: 10.1021/acs.joc.7b00299
Stacks Image 467
183 Hydrogen Borrowing Catalysis with Secondary Alcohols: A New Route for the Generation of β-Branched Carbonyl Compounds. Wasim M. Akhtar, Choon Boon Cheong, James R. Frost, Kirsten E. Christensen, Neil G. Stevenson, and Timothy J. Donohoe. J. Am. Chem. Soc., 2017, 139, 2577-2580. DOI: 10.1021/jacs.6b12840
Stacks Image 475
182 Diastereoselective synthesis of the 5-hydroxy-pyrrolidinone amino acid of the microsclerodermins and model studies for an end-game strategy for microsclerodermin B. Christian Winter, Robert D. C. Pullin and Timothy J. Donohoe. Tetrahedron Letters, 2017, 58, 602-605. DOI: 10.1016/j.tetlet.2016.12.045
Stacks Image 389
181 Orthogonally protected 1,2 diols from electron-rich alkenes using metal free olefin syn dihydroxylation. Ignacio Colomer, Rosimeire Coura Barcelos, Kirsten E. Christensen, Timothy J. Donohoe. Organic Letters, 2016, 18, 5880-5883. DOI: 10.1021/acs.orglett.6b02959
Stacks Image 391
180 Dehydromicrosclerodermin B and microsclerodermin J: total synthesis and structural revision
Ekaterina Y. Melikhova, Robert D. C. Pullin, Christian Winter, Timothy J. Donohoe. Angewandte Chemie Int. Ed., 2016, 55, 9753-9757. DOI: 10.1002/ange.201604764
Stacks Image 393
179 Hydrogen bonding to hexafluoroisopropanol controls the oxidative strength of hypervalent iodine reagents. Ignacio Colomer, Christopher Batchelor-McAuley, Barbara Odell, Timothy J. Donohoe, Richard Compton. J. Am. Chem. Soc. 2016,138, 8855-8861. DOI: 10.1021/jacs.6b04057
Stacks Image 397
178 Iridium-Catalyzed C4-Alkylation of 2,6-Di-tert-butylphenol using Hydrogen Borrowing Catalysis. James R. Frost, Choon Boon Cheong, Timothy J. Donohoe. Synthesis, 2016, 49, 910-916. DOI: 10.1055/s-0035-1561439
Stacks Image 399
177 Synthesis of aromatic heterocycles using ring-closing metathesis. Harish K. Potukuchi, Ignacio Colomer, Timothy J. Donohoe. Advances in Heterocyclic Chemistry: Alan Katritzky Tribute volume, Chapter 15, 2016, Elsevier, 43-65. DOI: 10.1016/bs.aihch.2016.04.006
Stacks Image 395
176 Catalytic hypervalent iodine promoters allow styrene dimerisation and the formation of tri- and tetrasubstituted cyclobutanes. Ignacio Colomer, Rosimeire Coura Barcelos and Timothy J. Donohoe. Angewandte Chemie Int. Ed., 2016, 55, 4748-4752. DOI: 10.1002/anie.201511683
Stacks Image 401
175 Palladium-catalysed enolate arylation as a key C-C bond forming reaction for the synthesis of isoquinolines. Ben S. Pilgrim, Alice E. Gatland, Carlos H. A. Estaves, Charlie T. McTernan, Geraint R. Jones, Matthew R. Tatton, Panayiotis A. Procopiou, Timothy J. Donohoe. Organic and Biomolecular Chemistry, 2016, 14, 1065-1090. Designated as a HOT article. DOI: 10.1039/C5OB02320C
Stacks Image 405
174 Strategic application and transformation of ortho-di-substituted phenyl and cyclopropyl ketones to expand the scope of hydrogen borrowing catalysis. James R. Frost, Choon Boon Cheong, Wasim M. Akhtar, Dimitri F. J. Caputo, Neil G. Stevenson and Timothy J. Donohoe. J. Am. Chem. Soc. 2016, 137, 15664-15667. DOI: 10.1021/jacs.5b11196
Stacks Image 403
173 Application of catalytic Z-selective olefin metathesis in natural product synthesis. Simon Werrel, Johannes C. L. Walker and Timothy J. Donohoe. Tetrahedron Letters, 2015, 56, 5261-5268. DOI: 10.1016/j.tetlet.2015.07.008
Stacks Image 407
172 Aziridine electrophiles in the functionalisation of peptide chains with amine nucleophiles. Anatol P. Spork and Timothy J. Donohoe. Organic and Biomolecular Chemistry, 2015, 13, 8545-8549. DOI: 10.1039/C5OB00856E
Stacks Image 409
171 Modular Synthesis of Highly Substituted Pyridines via Enolate α-Alkenylation. Leo A. Hardegger, Jacqueline Habegger and Timothy J. Donohoe. Organic Letters, 2015, 17, 3222-3225. DOI: 10.1021/acs.orglett.5b01312
Stacks Image 411
170 Palladium-catalyzed alpha-arylation of carbonyls in the de novo synthesis of aromatic heterocycles. Harish K. Potukuchi, Anatol P. Spork and Timothy J. Donohoe. Organic and Biomolecular Chemistry, 2015, 13, 4367-4373. DOI: 10.1039/C5OB00055F
Stacks Image 413
169 Hydrogen borrowing and interrupted hydrogen borrowing reactions of ketones and methanol, catalysed by iridium. Di Shen, Darren L. Poole, Camilla C. Shotton, Anne F. Kornahrens, Mark P. Healy and Timothy J. Donohoe. Angewandte Chemie Int. Ed., 2015, 54, 1642-1645. DOI: 10.1002/anie.201410391
Stacks Image 415
168 Short and efficient syntheses of protoberberine alkaloids using palladium catalyzed enolate arylation. Alice E. Gatland, Ben S. Pilgrim, Panayiotis A. Procopiou and Timothy J. Donohoe. Angewandte Chemie Int. Ed., 2014, 53, 14555-14558. DOI: 10.1002/anie.201409164
Stacks Image 417
167 Love-Hate ligands for high resolution analysis of strain in ultra-stable protein:small molecule interaction. Michael Fairhead, Di Shen, Louis K. M. Chan, Ed D. Lowe, Timothy J. Donohoe, Mark Howarth. Bioorganic & Medicinal Chemistry, 2014, 22, 5476-5486. DOI: 10.1016/j.bmc.2014.07.029
Stacks Image 419
166 New methods for the synthesis of naphthyl amines; application to the synthesis of dihydrosanguinarine, sanguinarine, oxysanguinarine and (±)-maclekarpines B and C. Matthew R. Tatton, Iain Simpson and Timothy J. Donohoe. Chem. Commun., 2014, 50, 11314-11316. DOI: 10.1039/C4CC05209A
Stacks Image 421
165 De novo Synthesis of Multi-Substituted Aryl Amines using Alkene Cross Metathesis. Matthew Tatton, Iain Simpson and Timothy J. Donohoe. Organic Letters, 2014, 16, 1920-1923. DOI: 10.1021/ol500441q
Stacks Image 425
164 Rhodium-Catalyzed Ketone Methylation Using Methanol Under Mild Conditions: Formation of Alpha-Branched Products. Louis K. M. Chan, Darren L. Poole, Di Shen, Mark P. Healy and Timothy J. Donohoe. Angewandte Chemie Int. Ed., 2014, 53, 761-765. Designated as a HOT paper, featured as the back cover. DOI: 10.1002/anie.201307950
Stacks Image 429
163 Total Synthesis of the Antitumor Antibiotic (+/-)-Streptonigrin: First and Second Generation Routes for de-novo Pyridine Formation using Ring Closing Metathesis. Timothy Donohoe, Christopher Jones, Anne Kornahrens, Luiz Barbosa, Louise Walport, Matthew Tatton, Michael O'Hagan, Akshat Rathi, David Baker. J. Org. Chem. 2013, 78, 12338-12350. Selected as a Featured Article. DOI: 10.1021/jo402388f
Stacks Image 423
162 Modular isoquinoline synthesis using catalytic enolate arylation and in-situ functionalization. Ben Pilgrim, Alice Gatland, Charlie McTernan, Panayiotis Procopiou, Timothy Donohoe. Organic Letters, 2013, 15, 6190-6193. DOI: 10.1021/ol4030309
Stacks Image 427
161 Tethered Aminohydroxylation: Synthesis of the β-Amino Acid of Microsclerodermins A and B. Robert D. C. Pullin , Akshat H. Rathi, Ekaterina Y. Melikhova, Christian Winter , Amber L. Thompson, and Timothy J. Donohoe. Org. Lett. 2013, 15, 5492-5495. DOI: 10.1021/ol402638n
Stacks Image 431
160 Lithium-4,4'-Di-tert-butylbiphenylide. Christopher R. Jones and Timothy J. Donohoe. Encyclopedia of Reagents for Organic Synthesis, 2013.
159 Vinyl Weinreb Amides: A Versatile Alternative to Vinyl Ketone Substrates for Heck Arylation. David B. Baker, Peter T. Gallagher and Timothy J. Donohoe. Tetrahedron 2013, 69, 3690-3697. DOI: 10.1016/j.tet.2013.03.009
Stacks Image 437
158 Osmium-Catalyzed Oxidative Cyclization of Dienes and Their Derivatives. Ben S. Pilgrim and Timothy J. Donohoe. J. Org. Chem. 2013, 78, 2149-2167. Work from this paper featured in the cover picture for JOC. DOI: 10.1021/jo302719y
Stacks Image 439
157 Interplay of cascade oxidative cyclisation and hydride shifts in the synthesis of the ABC spiroketal ring system of pectenotoxin-4. Timothy, J. Donohoe and Radek Lipinski. Angew. Chem. Int. Ed. 2013, 52, 2491-2494. Designated as a Hot Article. DOI: 10.1002/anie.201208919
Stacks Image 441
156 Oxidative cyclisation for the synthesis of complex THF-containing natural products. Timothy, J. Donohoe, Robert D. C. Pullin, Radoslaw M. Lipinski. Pure & Applied Chem. 2013, 85, 1175-1184. DOI: 10.1351/PAC-CON-12-10-25
Stacks Image 443
155 Partial and complete reduction of pyrroles, furans, thiophenes and their benzo-analogues and of aromatic heterocycles containing more than one heteroatom. Timothy J. Donohoe,* Christopher Jones and Christian Winter. Comprehensive Organic Synthesis II, Ed. G. Molander and P. Knochel, Elsevier, 2013.
154 Asymmetric Synthesis of the Fully Elaborated Pyrrolidone Core of Oxazolomycin A. Timothy J. Donohoe, Timothy J. C. O'Riordan, Manuel Peifer, Christopher R. Jones, Timothy J. Miles. Organic Lett. 2012, 14, 5460-5463. DOI: 10.1021/ol302541j
Stacks Image 445
153 Natural Product Synthesis as a Challenging Test of Newly Developed Methodology. Timothy J. Donohoe, Robert D. C. Pullin. Chemical Commun. 2012, 48, 11924-11938. DOI: 10.1039/C2CC36040C
Stacks Image 447
152 Synthesis of substituted isoquinolines utilizing palladium-catalyzed α-arylation of ketones. Timothy J. Donohoe, Ben S. Pilgrim, Geraint R. Jones and José A. Bassuto. Proc. Natl. Acad. Sci. US, 2012, 109, 11605-11608. DOI: 10.1073/pnas.1206532109
151 A green approach to Fenton chemistry: Hydroxylation of salicylic acid in aqueous medium using electrogeneration of Fenton's Reagent. Janjira Panchompoo, Leigh Aldous, Mikhail Kabeshov, Ben S. Pilgrim, Timothy J. Donohoe and Richard G. Compton. New. J. Chem. 2012, 36, 1265-1272. DOI: 10.1039/C2NJ21007J
Stacks Image 453
150 Hydrogen-Bonding-Mediated Directed Osmium Dihydroxylation. Timothy J. Donohoe, Carole J. R. Bataille, Paolo Innocenti. Organic Reactions, 2012, 76, 1-47. DOI: 10.1002/0471264180.or076.01
149 Olefin Cross-Metathesis for the Synthesis of Heteroaromatic Compounds. Timothy J. Donohoe, John F. Bower and  Louis K. M. Chan. Org. Biomol. Chem. 2012, 10, 1322-1328. Designated as a Hot Article. DOI: 10.1039/C2OB06659A
Stacks Image 449
148 Improvements in the Tethered Aminohydroxylation Reaction and its Application to Total Synthesis. Timothy J. Donohoe, Cedric K. A. Callens, Adam R. Lacy, Christian Winter. Eur. J. Org. Chem. 2012, 4, 655-663 (plus cover picture for this issue). DOI: 10.1002/ejoc.201101464
Stacks Image 455
147 Direct Preparation of thiazoles, imidazoles, imidazopyridines and thiazolidines from alkenes. Timothy J. Donohoe, Mikhail Kabeshov, Akshat Rathi and Ian E. D. Smith. Org. Biomol. Chem. 2012, 10, 1093-1101. DOI: 10.1039/C1OB06587D
Stacks Image 457
146 Tethered aminohydroxylation. Timothy J. Donohoe and Stefanie Mesch. Asymmetric Synthesis – The Essentials II. Edited by Mathias Christmann and Stefan Brase, WILEY-VCH, 2012, 17-26.
145 Amino acid based reoxidants for aminohydroxylation: application to the construction of amino acid-aminoalcohol conjugates. Timothy J. Donohoe, Cedric K. A. Callens, Aida Flores, Stefanie Mesch, Darren L. Poole and Ishmael A. Roslan. Angew. Chem. Int. Ed. 2011, 50, 10957-10960. DOI: 10.1002/anie.201103293
Stacks Image 459
144 Synthesis of 2,4,6-Trisubstituted Pyridines via an Olefin Cross-Metathesis/Heck-Cyclisation-Elimination Sequence. Timothy J. Donohoe, John F. Bower, David B. Baker, José A. Basutto, Louis K. M. Chan and Peter Gallagher. Chemical Commun. 2011, 47, 10611-10613. DOI: 10.1039/C1CC14257G
Stacks Image 461
143 Total synthesis of (±)-streptonigrin: de novo construction of a pentasubstituted pyridine using ring-closing metathesis. Timothy J. Donohoe, Christopher R. Jones, and Luiz C. A. Barbosa. J. Am. Chem. Soc. 2011, 133, 16418–16421. DOI: 10.1021/ja207835w
Stacks Image 463
142 Surface plasmon resonance imaging of glycoarrays identifies novel and unnatural carbohydrate-based ligands for potential ricin sensor development
Margherita Fais, Rositsa Karamanska, Sarah Allman, Shirley A. Fairhurst, Paolo Innocenti, Antony J. Fairbanks, Timothy J. Donohoe, Benjamin G. Davis, David A. Russell and Robert A. Field
Chemical Science, 2011, 2, 1952-1959.
DOI:
10.1039/C1SC00120E
141 The Influence of Exocyclic Stereochemistry on the Tethered Aminohydroxylation Reaction
Timothy J. Donohoe, Adam R. Lacy, Akshat H. Rathi, and Daryl S. Walter
Chemistry: An Asian Journal, 2011, 6, 3214-3222.
DOI:
10.1002/asia.201100497
140 A short and efficient synthesis of neodysiherbaine A using catalytic oxidative cyclisation
Timothy J. Donohoe, Paul Winship, Matthew R. Tatton and Peter Szeto
Angew. Chem. Int. Ed. 2011, 50, 7604-7606.
DOI:
10.1002/anie.201102525
139 Dehydrogenation of Cyclic-Thioethers Bound to a [Rh(diphosphine)]+ Fragment
Romeao Dallanegra, Ben S. Pilgrim, Adrian B. Chaplin, Timothy J. Donohoe and Andrew S. Weller
Dalton Transactions, 2011, 40, 6626-6628.
DOI:
10.1039/C1DT10503E
138 Exerting Control over the Acyloin Reaction
Timothy J. Donohoe, Ali Jahanshahi, Michael J. Tucker, Farrah L. Bhatti, Ishmael A. Roslan, Mikhail Kabeshov  and Gail Wrigley
Chemical Commun. 2011, 47, 5849-5851.
DOI:
10.1039/C1CC11654A
137 Intramolecular Hydride Addition to Pyridinium Salts: New Routes to Enantiopure Dihydropyridones
Timothy J. Donohoe, Matthew J. Connolly, Akshat H. Rathi and Lesley Walton
Organic Lett. 2011, 13, 2074-2077.
DOI: 
10.1021/ol200478p
136 Palladium nanoparticle-modified carbon nanotubes for electrochemical hydrogenolysis in ionic liquids
Yao Meng, Leigh Aldous, Ben S. Pilgrim, Timothy J. Donohoe and Richard G. Compton
New Journal of Chemistry, 2011, 35, 1369-1375.
DOI:
10.1039/C1NJ20070D
135 Heteroaromatic Synthesis via Olefin Cross-Metathesis: Entry to Polysubstituted Pyridines
Timothy J. Donohoe, José Basutto, Akshat H. Rathi and John F. Bower
Organic Lett. 2011, 13, 1036-1039.
DOI:
10.1021/ol103088r
134 Recent Developments in Methodology for the Direct Oxyamination of Olefins
Timothy J.  Donohoe, Aida Flores, Cedric K.A. Callens, Adam J. Lacy, Akshat H. Rathi
Chem. Eur. J., 2011, 17, 58-76.
DOI:
10.1002/chem.201002323
133 Osmium-free direct syn-dihydroxylation of alkenes
Carole J. R. Bataille and Timothy J. Donohoe
Chem. Soc. Rev. 2011, 40, 114-128.
DOI: 
10.1039/B923880H
132 Direct preparation of heteroaromatic compounds from alkenes
Timothy J. Donohoe, Mikhail A. Kabeshov, Akshat H. Rathi and Ian E.D. Smith
Synlett, 2010, 19, 2956-2958.
DOI:
10.1055/s-0030-1259034
131 Identification of Epigenetic DNA Modifications with a Protein Nanopore
Emma V. B. Wallace, David Stoddart, Andrew J. Heron, Ellina Mikhailova, Giovanni Maglia, Timothy J. Donohoe, Hagan Bayley  
Chemical Commun. 2010, 46, 8195-8197.
DOI:
10.1039/C0CC02864A
130 A Novel Oxidative Cyclisation onto Vinyl Silanes
Timothy J. Donohoe, Paul C. M. Winship, Ben S. Pilgrim, Daryl S. Walter, Cedric K. A. Callen
Chemical Commun. 2010, 46, 7310-7312.
DOI:
10.1039/c0cc01342k
129 Olefin cross-metathesis based approaches to furans: procedures for the preparation of di- and trisubstituted variants
Timothy J. Donohoe, John F. Bower and José A. Basutto
Nature: Protocols, 2010, 5, 2005-2010.
DOI:
10.1038/nprot.2010.147
128 Substituted Pyrroles via Olefin Cross-Metathesis
Timothy J. Donohoe, Nicholas J. Race, John F. Bower and Cedric K. A. Callens
Organic Lett. 2010, 12, 4094-4097.
DOI:
10.1021/ol101681r
127 Synthesis of cylindricine C and a formal synthesis of cylindricine A
Timothy J. Donohoe, Ptoton M. Brian, Gráinne C. Hargaden and Timothy J.C. O'Riordan
Tetrahedron (Steven Ley Prize Issue), 2010, 66, 6411-6420.
DOI:
10.1016/j.tet.2010.05.044
126 An expedient route to substituted furans via olefin cross metathesis
Timothy J. Donohoe and John F. Bower
Proc. Natl. Acad. Sci. US, 2010, 107, 3373-3376.
This work has been highlighted in PNAS, Science and Nature Chemistry journals with a commentary.
DOI:
10.1073/pnas.0913466107
125 New modes for the osmium-catalyzed oxidative cyclization
Timothy. J. Donohoe, Cedric K.A. Callens, Jeremy Parker and Peter J. Lindsay-Scott
Organic Lett. 2010, 12, 1060-1063.
This paper was recently highlighted in the literature, see: Synfacts, 2010, 6, 683.
DOI:
10.1021/ol100046a
124 Regioselective nucleophilic addition to pyridinium salts: a new route to substituted dihydropyridones
Timothy J. Donohoe, Matthew J. Connolly and Lesley Walton
Organic Lett. 2009, 11, 5562-5565.
DOI:
I:10.1021/ol902402v
123 Author profile
Timothy J. Donohoe
Angew. Chem. Int. Ed. 2009, 48, 7119.
DOI:
10.1002/anie.200903879
122 Ring-closing metathesis for the synthesis of heteroaromatics: evaluating routes to pyridines and pyridazines
Timothy J. Donohoe, John F. Bower, José A. Basutto, Lisa P. Fishlock, Panayiotis A. Procopiou and Cedric K.A. Callens
Tetrahedron, 2009, 8969–8980.
DOI:
10.1016/j.tet.2009.07.076
121 Concise syntheses of the natural products (+)-sylvaticin and (+)-cis-sylvaticin
Timothy J. Donohoe, Robert M. Harris, Oliver Williams, Grainne C. Hargaden, Jeremy Burrows, Jeremy Parker
J. Am. Chem. Soc. 2009, 131, 12854-12861.
DOI:
10.1021/ja9049959
120 Synthesis of (–)-Hygromycin A: Application of Mitsunobu Glycosylation and Tethered Aminohydroxylation
Timothy J. Donohoe, Aida Flores, Carole J. Bataille and Fátima Churruca
Angew. Chem. Int. Ed. 2009, 48, 6507-6510.
DOI:
10.1002/ange.200902840
119 A Lewis Acid Promoted Oxidative Cyclisation
Timothy J. Donohoe, Paul C. M. Winship and Daryl S. Walter
J. Org. Chem. 2009, 74, 6394-6397.
DOI:
10.1021/jo901243y
118 Osmium-mediated Oxidative Cyclisations: a study into the range of initiators that facilitate cyclisation
Timothy J. Donohoe, Katherine M. P. Wheelhouse (née Gosby), Peter J. Lindsay-Scott, Gwydion H. Churchill, Matthew J. Connolly, Sam Butterworth and Paul A. Glossop
Chemistry: An Asian Journal, 2009, 4, 1237-1247.
DOI:
10.1002/asia.200900168
117 Electrochemistry in tetrahydrofuran and at low temperature: protocol, procedures and methods
Ronan Baron, Neil M. Kershaw, Timothy J. Donohoe and Richard G. Compton
Journal of Phys. Org. Chem. 2009, 22, 1136-1141.
DOI:
10.1002/poc.1574
116 The tethered aminohydroxylation (TA) reaction of amides
Timothy J. Donohoe, Cedric K.A. Callens and Amber L. Thompson
Organic Lett. 2009, 11, 2305-2307.
DOI:
10.1021/ol900631y
115 The effect of ortho-substitution on the efficacy of biphenyls in mediating electron transfer from lithium
Timothy J. Donohoe, Neil M. Kershaw, Ronan Baron and Richard G. Compton
Tetrahedron, 2009, 65, 5377-5384.
DOI:
10.1016/j.tet.2009.04.057
114 Synthesis of substituted pyridines and pyridazines via ring closing metathesis
Timothy J. Donohoe, Lisa P. Fishlock, José A. Basutto, John F. Bower, Panayiotis A. Procopiou and Amber L. Thompson  
Chemical Commun. 2009, 21, 3008-3010.
DOI:
10.1039/b904363b
113 Tandem catalysis in the polycyclisation of dienes to produce multi-substituted tetrahydrofurans
Timothy J. Donohoe, Peter J. Lindsay-Scott and Jeremy S. Parker
Tetrahedron Letters, 2009, 50, 3523-3526.
DOI:
10.1016/j.tetlet.2009.03.027
112 Ruthenium catalysed isomerization of terminal Olefins: applications to synthesis
Timothy J. Donohoe, Timothy J.C. O'Riordan and Carla P. Rosa
Angew. Chem. Int. Ed. 2009, 48, 1014-1017.
DOI:
10.1002/anie.200804617
111 Quantitative voltammetry of the reduction of methyl benzoate in THF reveals strong ion pairing of the radical anion with tetra-n-butyl cations
Ronan Baron, Neil M. Kershaw, Timothy J. Donohoe and Richard G. Compton
Journal of Phys. Org. Chem. 2009, 22, 247-253.
DOI:
10.1002/poc.1462
110 Synthesis of (+)-DGDP and (–)-7-Epialexine
Timothy J. Donohoe, Matthew D. Cheeseman, Timothy J.C. O'Riordan and Jessica A. Kershaw
Org. Biomol. Chem. 2008, 6, 3896-3898.
DOI:
10.1039/b815332a
109 Alkali metal reductions of organic molecules: why mediated electron transfer from Lithium is faster than direct reduction
Neil Rees, Ronan Baron, Neil Kershaw, Timothy J. Donohoe, Richard J. Compton
J. Am. Chem. Soc. 2008, 130, 12256-12257.
DOI:
10.1021/ja805086w
108 Flexible strategy for the synthesis of pyrrolizidine alkaloids
Timothy J. Donohoe, Rhian Thomas, Matthew Cheeseman, Caroline Rigby, Ian Linney and Gurdip Bhalay
Organic Lett. 2008, 10, 3615-3618.
DOI:
10.1021/ol801415d
107 Synthesis of (–)-(Z)-deoxypukalide
Timothy J. Donohoe, Alan Ironmonger and Neil M. Kershaw
Angew. Chem. Int. Ed. 2008, 47, 7314-7316.
DOI:
10.1002/anie.200802703
106 Ring-Closing Metathesis as a Key Step in the Synthesis of 2-Pyridones and Pyridine Triflates
Timothy J. Donohoe, Lisa P. Fishlock and Panayiotis A. Procopiou
Synthesis, 2008, 129, 2665-2667 (Practical Synthetic Procedure)
DOI:
10.1055/s-2008-1067180
105 Ring-closing metathesis: novel routes to aromatic heterocycles
Timothy J. Donohoe, Lisa P. Fishlock and Pan A. Procopiou
Chemistry: A European Journal, 2008, 14, 5716-5726
DOI:
10.1002/chem.200800130
104 Pyridine-N-Oxide as a mild reoxidant which transforms Osmium catalysed oxidative cyclisation
Timothy J. Donohoe, Katherine M.P. Wheelhouse (née) Gosby, Peter J. Lindsay-Scott, Paul A. Glossop, Ian A. Nash and Jeremy S. Parker
Angew. Chem. Int. Ed. 2008, 47, 2872-2875.
DOI:
10.1002/anie.200705425
103 Hydride shift generated oxonium ions: evidence for mechanism and intramolecular trapping experiments to form trans THF derivatives
Timothy J. Donohoe, Oliver Williams and Gwydion H. Churchill
Angew. Chem. Int. Ed. 2008, 47, 2869-2871.
DOI:
10.1002/anie.200705340
102 A metathesis-based approach to the synthesis of 2-Pyridones and Pyridines
Timothy J. Donohoe, Lisa P. Fishlock and Pan A. Procopiou
Organic Lett. 2008, 10, 285-288.
DOI:
10.1021/ol702684d
101 Flexible metathesis-based approaches to highly functionalised furans and pyrroles
Timothy J. Donohoe, Neil M. Kershaw, Allan J. Orr, Katherine M. P. Wheelhouse (née Gosby), Lisa P. Fishlock, Adam R. Lacy, Matilda Bingham and Panayiotis A. Procopiou
Tetrahedron, 2008, 64, 809-820.
DOI:
10.1016/j.tet.2007.09.087
100 Electrosynthetic reduction of 1-iodoadamantane forming 1,1'-biadamantane and adamantane in aprotic solvents: Insonation switches the mechanism from dimerisation to exclusive monomer formation
Christopher A. Paddon, Farrah L. Bhatti, Timothy J. Donohoe and Richard G. Compton
Ultrasonics Sonochemistry, 2007, 14, 502-508.
DOI:
10.1016/j.ultsonch.2006.11.007
99 Cryoelectrochemical reduction of a phenyl sulfide in tetrahydrofuran: mediated reduction gives different products compared to direct reduction  
Alexander V. Burasov, Christopher A. Paddon, Farrah L. Bhatti, Timothy J. Donohoe and Richard G. Compton  
J. Phys. Org. Chem. 2007, 20, 144-150.
DOI:
10.1002/poc.1138
98 Electrocatalytic reduction of alkyl iodides in tetrahydrofuran at silver electrodes
Christopher A. Paddon, Farrah L. Bhatti, Timothy J. Donohoe and Richard G. Compton
J. Phys. Org. Chem. 2007, 20, 115-121.
DOI:
10.1002/poc.1133
97 Kinetics and thermodynamics of the Li/Li+ couple in tetrahydrofuran at low temperatures (195-295 K)  
Christoper A. Paddon, Sarah E. Ward Jones, Farrah L. Bhatti, Timothy J. Donohoe and Richard G. Compton
J. Phys. Org. Chem. 2007, 20, 677-684.
DOI:
10.1002/poc.1230
96 A concise and efficient synthesis of (-)-Allosamizoline
Timothy J. Donohoe and Carla P. Rosa
Organic Lett. 2007, 9, 5509-5511.
DOI:
10.1021/ol702449m
95 Mediated electron transfer from lithium investigated voltammetrically in tetrahydrofuran: why are some mediators more effective reducing reagents than others?
Natasha C.L. Wood, Christopher A. Paddon, Farrah L. Bhatti, Timothy J. Donohoe and Richard G. Compton
J. Phys. Org. Chem. 2007, 20, 732-742.
DOI:
10.1002/poc.1232
94 The partial reduction of electron-deficient pyrroles: procedures describing both Birch (Li/NH3) and ammonia-free (Li/DBB) conditions
Timothy J. Donohoe, Rhian E. Thomas
Nature: Protocols, 2007, 2, 1888-1895.
Cover picture for this issue
DOI:
10.1038/nprot.2007.245
93 The Tethered Aminohydroxylation: Dramatic Improvements to the Process
Timothy J. Donohoe, Carole J. R. Bataille, William Gattrell, Johannes Kloesges and Emilie Rossignol
Organic Lett. 2007, 9, 1725-1728.
DOI:
10.1021/ol070430v
92 A Metathesis Based Approach to the Synthesis of Furans
Timothy J. Donohoe, Lisa P. Fishlock, Adam R. Lacy, and Panayiotis A. Procopiou
Organic Lett. 2007, 9, 953-956.
DOI:
10.1021/ol062933r
91 Coulometry on the Voltammetric Timescale: Microdisk Potential-Step Chronoamperometry in Aprotic Solvents Reliably Measures the Number of Electrons Transferred in an Electrode Process Simultaneously with the Diffusion Coefficients of the Electroactive species
Christopher A. Paddon, Debbie S. Silvester, Farrah L. Bhatti, Timothy J. Donohoe, Richard G. Compton
Electroanalysis, 2007, 19, 11-22.
DOI:
0.1002/elan.200603667
90 Partial Reduction of Pyrroles: Application to Natural Product Synthesis
Timothy J. Donohoe, and Rhian E. Thomas
The Chemical Record, 2007, 7, 180-190.
DOI:
10.1002/tcr.20115
89 Synthesis of the Pyrrolidinone Core of KSM-2690 B
Timothy J. Donohoe, Jessica Chiu, Rhian E Thomas
Organic Lett. 2007, 9, 421-424.
DOI:
10.1021/ol062705x
88 Total Synthesis of (+)-cis-Sylvaticin: Double Oxidative Cyclisation Reactions Catalyzed by Osmium
Timothy J. Donohoe, Robert M. Harris, Jeremy Burrows and Jeremy Parker
J. Am. Chem. Soc. 2006, 128, 13704-13705.
DOI:
10.1021/ja0660148
87 Stereoselective Synthesis of Pyrrolidines: Catalytic Oxidative Cyclisations Mediated by Osmium
Timothy J. Donohoe, Gwydion H. Churchill, Katherine M. P. Wheelhouse (née Gosby) and Paul A. Glossop
Angew. Chem. Int. Ed. 2006, 45, 8025-8028.
DOI:
10.1002/anie.200603240
86 Cryo-electrochemistry in tetrahydrofuran: The regioselective electrochemical reduction of a phenyl sulfone: Fast-scan cyclic voltammetry investigations
Nicole Fietkaua, Christopher A. Paddon, Farrah L. Bhattib, Timothy J. Donohoe and Richard G. Compton
Journal of Electroanalytical Chemistry 2006, 593, 131-141.
DOI:
10.1016/j.jelechem.2006.03.004
85 Cryovoltammetrically probing functional group reductive cleavage: Alkyl-sulfur versus aryl-sulfur bond cleavage in an alkyl naphthyl thioether under single electron transfer is temperature switchable
Christopher A. Paddon, Farrah L. Bhatti, Timothy J. Donohoe and Richard G. Compton
Chem. Commun. 2006, 3402-2404.
DOI:
10.1039/B606638K
84 Highlights of Natural Product Synthesis
Timothy J. Donohoe, Carole J. R. Bataille and Gwydion H. Churchill
Annual Rep. Prog. Chem. Sect. B, 2006, 102, 98-122.
DOI:
10.1039/B515095G
83 An Enzymatic Approach to the Desymmetrisation of Disubstituted Pyrrolines
Timothy J. Donohoe, Caroline L. Rigby, Rhian E. Thomas, William F. Nieuwenhuys, Farrah L. Bhatti, Andrew R. Cowley, Gurdip Bhalay and Ian D. Linney
J. Org. Chem. 2006, 71, 6298-6301.
DOI:  
10.1021/jo060926a
82 Cryo-electrochemistry in tetrahydrofuran: The electrochemical reduction of a phenyl thioether: [(3-{[ trans -4-(Methoxymethoxy)cyclohexyl]oxy}propyl)thio]benzene
Christopher A. Paddon, Farrah L. Bhatti, Timothy J. Donohoe and Richard G. Compton
Journal of Electroanalytical Chemistry, 2006, 589, 187-194.
DOI:
10.1016/j.jelechem.2006.02.010
81 New Osmium-Based Reagent for the Dihydroxylation of Alkenes
Timothy J. Donohoe, Robert M. Harris, Sam Butterworth, Jeremy N. Burrows, Andrew Cowley, and Jeremy S. Parker
J. Org. Chem. 2006, 71, 4481-4489.
DOI:
10.1021/jo060301c
80 N-Sulfonyloxy Carbamates as Re-oxidants for the Tethered Aminohydroxylation Reaction
Timothy J. Donohoe, Majid J. Chughtai, David J. Klauber, David Griffin and Andrew D. Campbell
J. Am. Chem. Soc. 2006, 128, 2514-2515.
DOI: 10.1021/ja057389g
79 The Ammonia-Free Partial Reduction of Substituted Pyridinium Salts
Timothy J. Donohoe, Dale J. Johnson, Laura H. Mace, Rhian E. Thomas, Jessica Y. K. Chiu, Jason S. Rodrigues, Richard G. Compton, Craig E. Banks, Peter Tomcik, Mark J. Bamford and Osamu Ichihara
Org. Biomol. Chem. 2006, 4, 1071-1084.
DOI:
10.1039/B517462G
78 Ring Closing Metathesis as a Basis for the Construction of Aromatic Compounds
Timothy J. Donohoe,* Allan J. Orr and Matilda Bingham
Angew. Chem. Int Ed. 2006, 45, 2664-2670.
DOI:
10.1002/anie.200503512
77 A non-carbohydrate based approach to polyhydroxylated pyrrolidizines; total syntheses of the natural products hyacinthacine A1 and 1-epiaustraline
Timothy J. Donohoe, Herman O. Sintim and Jackie Hollinshead
J. Org. Chem. 2005, 70, 7297-7304.
DOI:
10.1021/jo050977s
76 Oxidative cyclisations of diols derived from 1,5-dienes: formation of enantiopure cis-tetrahydrofurans using catalytic osmium tetroxide and a formal synthesis of (+)-cis-solamin
Timothy J. Donohoe and Sam Butterworth
Angew. Chem. Int. Ed. 2005, 44, 4766-4768.
DOI: 
10.1002/anie.200500513
75 A Metathesis Approach to Aromatic Heterocycles
Timothy J. Donohoe, Allan J. Orr, Katherine Gosby and Matilda Bingham
Eur. J. Org. Chem. 2005, 1969-1971.
DOI:
10.1002/ejoc.200500113
74 A Concise and Enantioselective Synthesis of the Aminocyclitol Core of Hygromycin A
Timothy J. Donohoe, Peter D. Johnson, Richard J. Pye and Martine Keenan
Organic Lett. 2005, 7, 1275-1277.
DOI:
10.1021/ol0473750
73 Utility of the ammonia-free Birch reduction of electron-deficient pyrroles: total synthesis of the 20S proteasome inhibitor, clasto-lactacystin beta-lactone
Timothy J. Donohoe, Herman O. Sintim, Leena Sisangia, Karl W. Ace, Paul M. Guyo, Andrew Cowley and John D. Harling
Chemistry: A European Journal, 2005, 11, 4227-4238.
DOI:
10.1002/chem.200401119
72 Partial Reduction of Pyridinium Salts as a Versatile Route to Dihydropyridones
Timothy J. Donohoe, D. Johnson, L. H. Mace, O. Ichihara and M. Bamford
Organic Lett. 2005, 7, 453-437.
DOI:
10.1021/ol0476624
71 Cryoelectrochemistry: Electrochemical reduction of 2(RS)-Methyl 1-(tert-butoxycarbonyl)-2-iodomethyl-2,5-dihydropyrrole-2-carboxylate
Craig E. Banks, Russell G. Evans, Jason Rodrigues, Peter G. Turner, Timothy J. Donohoe and Richard G. Compton
Tetrahedron, 2005, 61, 2365-2372.
DOI:
10.1016/j.tet.2005.01.022
70 Enantioselective Partial Reduction of 2,5-Disubstituted Pyrroles via a Chiral Protonation Approach
Timothy J. Donohoe, Catherine E. Headley, Caroline L. Rigby, Graeme C. Freestone, Rick P. C. Cousins and Gurdip Bhlay
Organic Lett. 2004, 6, 3055-3058.
DOI:  
10.1021/ol049014q
69 Efficient Acyclic Stereocontrol Using the Tethered Aminohydroxylation Reaction
Timothy J. Donohoe, Peter D. Johnson, Martine Keenan and Richard J. Pye
Organic Lett. 2004, 6, 2583-2585.
DOI:
10.1021/ol049136i
68 An Efficient Synthesis of (±)-1 Epiaustraline
Timothy J. Donohoe and Herman O. Sintim
Organic Lett. 2004, 6, 2003-2006.
DOI:
10.1021/ol049397s
67 Rearrangement of Pyrrolines Derived from the Birch Reduction of Electron-Deficient Pyrroles: Radical Ring-Expansion to Substituted Tetrahydropyridines
Timothy J. Donohoe, Rick P. C. Cousins and Peter Turner
Chem. Commun. 2004, 1422-1423.
DOI:
10.1039/B404002C
66 Low Temperature Electrochemistry as a Mechanistic Probe for the Partial Reduction of Heterocycles
Timothy J. Donohoe, Richard Compton, Dale Johnson and Jay D. Wadhawan
Tetrahedron, 2004, 60, 5945-5952.
DOI:
10.1016/j.tet.2004.05.027
65 An Efficient Synthesis of Lactacysin ß-Lactone
Timothy J. Donohoe, Leena Sisangia, Herman O. Sintim and John D. Harling
Angew. Chem. Int. Ed. 2004, 43, 2293-2296.
DOI: 
10.1002/anie.200453843
64 Enantiopure Oxazolidinones as Chiral Acids in the Asymmetric Protonation of N-Boc Pyrrole Derived Enolates
Timothy J. Donohoe and David Carbery
Chem. Commun. 2004, 722-723.
DOI:
10.1039/B316719D
63 Synthesis of (±)-Secosyrin 1 and a Formal Synthesis of (–)-Secosyrin 1
Timothy J. Donohoe, John W. Fisher and Paul J. Edwards
Organic Lett. 2004, 6, 465-467.
DOI:
10.1021/ol0362313
62 Trichloro-oxazolines as activated donors for aminosugar coupling
Timothy J. Donohoe, James G. Logan and David D. P. Laffan
Organic Lett. 2003, 5, 4995 - 4998.
DOI:
10.1021/ol0359620
61 Calcium mobilisation and CCK secretion induced by modified fatty acids and latex microspheres reveal dual receptor mechanisms for lipid stimulation of STC-1 cells.
S. Kazmi, R. S. P. Benson, T. J. Donohoe, M. N. Jones, M. Wickham, D. G. Thompson, R. M. Case
Journal of Physiology, 2003, 553, 759-773.
DOI:
10.1113/jphysiol.2003.051680
60 Osmium Tetroxide
Timothy J. Donohoe, Robert Harris and Majid Chugtai
Encyclopedia of Reagents for Organic Synthesis, 2003.
DOI:
10.1002/047084289X.ro007.pub2
59 Scope of the Reductive Aldol Reaction: Application to Aromatic Carbocycles and Heterocycles
Timothy J. Donohoe, David House and K. W. Ace
Org. Biomol. Chem. 2003, 3749-3757.
DOI:
10.1039/B306937K
58 The Tethered Aminohydroxylation (TA) Reaction
Timothy J. Donohoe, Peter D. Johnson and Richard J. Pye
Org. Biomol. Chem. 2003, 1, 2025-2028.
DOI:
10.1039/b305189g 
57 Scope of the Directed Dihydroxylation: Application to Cyclic Homoallylic Alcohols and Trihaloacetamides
Timothy J. Donohoe, Lee Mitchell, Michael J. Waring, Madeleine Helliwell, Andrew Bell, and Nicholas J. Newcombe
Org. Biomol. Chem. 2003, 1, 2173-2186.
DOI:
10.1039/b303081d 
56 Flexibility in the Partial Reduction of 2,5-Disubstituted Pyrroles: Application to the Synthesis of DMDP
Timothy J. Donohoe, Catherine E. Headley, Rick P. C. Cousins and Andrew Cowley
Organic Lett. 2003, 5, 999-1002.
DOI:
10.1021/ol027504h
55 A General Oxidative Cyclisation of 1,5-Dienes Using Catalytic Osmium Tetroxide
Timothy J. Donohoe and Sam Butterworth
Angew. Chem. Int. Ed. 2003, 42, 948-951.
DOI:
10.1002/anie.200390253
54 Diastereoselective reductive aldol reactions of BOC-protected electron deficient pyrroles
Timothy J. Donohoe and David House
Tetrahedron Letters, 2003, 44, 1095-1098.
DOI:
10.1016/S0040-4039(02)02672-2
53 The Directed Dihydroxylation of Cyclic Allylic Alcohols and Trichloroacetamides Using OsO4/TMEDA
Timothy J. Donohoe, Kevin Blades, Peter R. Moore, Michael J. Waring, Jon J. G. Winter, Madeleine Helliwell, Nicholas J. Newcombe and Geoffrey Stemp
J. Org. Chem. 2002, 67, 7946-7956.
DOI:
10.1021/jo026161y
52 The Tethered Aminohydroxylation (TA) of Cyclic Allylic Carbamates
Timothy J. Donohoe, Peter D. Johnson, Andrew Cowley and Martine Keenan
J. Am. Chem. Soc. 2002, 124, 12934-12935.
DOI:
10.1021/ja0276117
51 Synthesis of enantiopure dihydropyranones: aldol-based ring expansion of dihydrofurans
Timothy J. Donohoe, Ali Raoof, Graeme C. Freestone, Ian D. Linney, Andrew Cowley and Madeleine Helliwell
Organic Lett. 2002, 4, 3059-3062.
DOI:
10.1021/ol0263595
50 Partial reduction of 3-heteroatom substituted 2-furoic acids: the role of an ortho group on viability and stereoselectivity
Timothy J. Donohoe, Andrew A. Calabrese, Jean-Baptiste Guillermin, Christopher. S. Frampton and Daryl Walter
J. Chem. Soc. Perkin Transactions 1, 2002, 1748-1756.
DOI:
10.1039/B203437A
49 Ammonia Free Reduction of Aromatic Compounds Using Lithium Di-tert-butylbiphenyl (LiDBB)
Timothy J. Donohoe and David House
J. Org. Chem. 2002, 67, 5015-5018.
DOI:  
10.1021/jo0257593
48 Preparation of (+)-Nemorensic Acid and Approaches to Nemorensine using the Partial Reduction of Electron Deficient Furans
Timothy J. Donohoe, Jean-Baptiste Guillermin and Daryl S. Walter
J. Chem. Soc. Perkin Transactions 1, 2002, 1369-1375.
DOI: 10.1039/B202514K
47 Development of the Directed Dihydroxylation Reaction
Timothy J. Donohoe
Synlett, 2002, 8, 1223-1232.
DOI:
10.1055/s-2002-32947
46 Transformations of 3,4-disubstituted pyridines under dissolving metal conditions-partial reduction followed by radical cyclisation
Timothy J Donohoe, Laura Mace, Madeleine Helliwell and Osamu Ichihara
Synlett, 2002, 331-333.
DOI:
10.1055/s-2002-19757
45 Homoallylic alcohols and trichloroacetamides as hydrogen bond donors for directed dihydroxylation
Timothy J. Donohoe, L. Mitchell, M. J. Waring, M. Helliwell, A. Bell and N. J. Newcombe
Tetrahedron Letters, 2001, 42, 8951-8954.
DOI:
10.1016/S0040-4039(01)01999-2
44 The Regioselective Aminohydroxylation of Allylic Carbamates
Timothy J. Donohoe, Peter D. Johnson, Madeleine Helliwell, and Martine Keenan
Chem. Commun. 2001, 2078.
DOI:
10.1039/B107253F
43 Silyl substituted furans in the stereoselective Birch reduction
Timothy J Donohoe, Andrew A. Calabrese, Jean-Baptiste Guillermin and Daryl S. Walter
Tetrahedron Letters, 2001, 42, 5841.
DOI:
10.1016/S0040-4039(01)01151-0
42 Use of Dissolving Metals in the Partial Reduction of Pyridines: Formation of 2-Alkyl-1,2-Dihydropyridines
T. J. Donohoe, Andrew J. McRiner, Madeleine Helliwell and Peter Sheldrake
J. Chem. Soc. Perkin Transactions 1, 2001, 1435-1445.
DOI:
10.1039/B101662H
41 Partial Reduction of Annulated Heterocycles as a General Route to Medium Rings Containing Oxygen and Nitrogen
Timothy J. Donohoe, Ali Raoof, Ian D. Linney and Madeleine Helliwell
Organic Lett. 2001, 3, 861-864.
DOI:
10.1021/ol007035o
40 Hydrogen bonding control in the oxidative cyclisation of 1,5-dienes
Timothy J. Donohoe, Jonathan J. G. Winter, M. Helliwell and Geoffrey Stemp
Tetrahedron Letters, 2001, 42, 971-974.
DOI:
10.1016/S0040-4039(00)02225-5
39 Partial Reduction of Electron-Deficient Pyridines
T. J. Donohoe, A. J. McRiner and P. Sheldrake
Organic Lett. 2000, 2, 3861-3863.
DOI:
10.1021/ol0065930
38 Stereoselective Reduction of Chiral 2-Furoic Acid Derivatives Using Group I Metals in Ammonia
Timothy J. Donohoe, Andrew A. Calabrese, Clare A. Stevenson and Tamara Ladduwahetty
J. Chem. Soc. Perkin Transactions 1, 2000, 3724.
DOI:
10.1039/B006390H
37 Oxidation and Reduction in Organic Synthesis: OUP Chemistry Primer No. 6
Timothy J. Donohoe
Oxford University Press, 2000, ISBN 0198556640.
36 A Syn Selective Dihydroxylation of Cyclic Allylic Trichloroacetamides Using Catalytic Osmium Tetroxide
Kevin Blades, Timothy J. Donohoe, Jonathan J. G. Winter and Geoffrey Stemp
Tetrahedron Letters, 2000, 41, 4701-4704.
DOI:
10.1016/S0040-4039(00)00714-0
35 The Synthesis of (+)-Nemorensic Acid
Timothy J. Donohoe, J. -B. Guillermin, C. Frampton and D. S. Walters
J. Chem Soc., Chem. Commun. 2000, 465-466.
DOI:
10.1039/B000565G
34 The partial reduction of heterocycles: an alternative to the Birch reduction
Timothy J. Donohoe, Rakesh R. Harji and Rick P. C. Cousins
Tetrahedron Letters, 2000, 41, 1331-1334.
DOI:
10.1016/S0040-4039(99)02315-1
33 Stereoselective Reductive Alkylation of 2,5-disubstituted Pyrroles: A Role for Naphthalene in the Partial Reduction of Heterocycles
Timothy J. Donohoe, Rakesh R. Harji and Rick P. C. Cousins
Tetrahedron Letters, 2000, 41, 1327-1330.
DOI:
10.1016/S0040-4039(99)02314-X
32 Reductive Aldol Reactions on Aromatic Heterocycles
Timothy J. Donohoe, Karl W. Ace, Paul M. Guyo, Madeleine Helliwell and Jeffrey McKenna
Tetrahedron Letters, 2000, 41, 989-993.
DOI:
10.1016/S0040-4039(99)02224-8
31 Enhanced Stereoselectivity in the Catalytic Dihydroxylation of Acyclic Allylic Alcohols
Timothy J. Donohoe, Michael J. Waring, and Nicholas J. Newcombe
Synlett, 2000, 149-151.
DOI:
10.1055/s-2000-6457
30 1H- and 2H-Isoindoles
Timothy J. Donohoe
Science of Synthesis, Georg Thieme Verlag, 2000, Volume 10, 653-692. (Review)
29 Birch Reduction of Aromatic Heterocycles
Timothy J. Donohoe, P. M. Guyo and A. Raoof
Targets in Heterocyclic Systems, Italian Society of Chemistry, 1999, 3, 117-145 (Review).
28 Syn Stereocontrol in the Directed Dihydroxylation of Ayclic Allylic Alcohols
Timothy J. Donohoe, Michael J. Waring and Nicholas J. Newcombe
Tetrahedron Letters, 1999, 40, 6881-6884.
DOI:
10.1016/S0040-4039(99)01371-4
27 The Synthesis of (–)-cis and (–)-trans-Crobarbatic Acid
Timothy J. Donohoe, C. A. Stevenson M. Helliwell, R. Irshad and T. Ladduwahetty
Tetrahedron: Asymmetry, 1999, 10, 1315-1320.
DOI:
10.1016/S0957-4166(99)00097-X
26 Directed Dihydroxylation of Allylic Trichloroacetamides
Timothy J. Donohoe, Kevin Blades, Peter R. Moore, Jonathan J. G. Winter, Madeleine Helliwell and Geoffrey Stemp
J. Org. Chem. 1999, 64, 2980-2981.
DOI:
10.1021/jo982468e
25 Stereoselectivity in the double reductive alkylation of pyrroles: synthesis of cis-3,4-disubstituted pyrrolidines
Timothy J. Donohoe, Rakesh R. Harji and Rick P. C. Cousins
J. Chem Soc., Chem. Commun. 1999, 141-142.
DOI:
10.1039/A809193E
24 The Stereoselective Birch Reduction of Pyrroles
Timothy J. Donohoe, P. M. Guyo and M. Helliwell
Tetrahedron Letters, 1999, 40, 435-438.
DOI:
10.1016/S0040-4039(98)02395-8
23 Synthesis of Amino-Sugars Using the Directed Dihydroxylation Reaction
Timothy J. Donohoe, Kevin Blades and Madeleine Helliwell
J. Chem Soc., Chem. Commun. 1999, 1733-1734.
DOI:
10.1039/A904991F
22 The Synthesis of (+)-pericosine B
Timothy J. Donohoe, K. Blades, M. Helliwell, M. J. Waring, and N. J. Newcombe
Tetrahedron Lett. 1998, 39, 8755-8758.
DOI:
10.1016/S0040-4039(98)01989-3
21 The Birch Reduction of 3-Substituted Pyrroles
Timothy J. Donohoe, P. M. Guyo, R. R. Harji and R. P. C. Cousins
Tetrahedron Lett. 1998, 39, 3075-3078.
DOI: 10.1016/S0040-4039(98)00362-1
20 Stereoselectivity in the Birch Reduction of 2-Furoic Acid Derivatives
Timothy J. Donohoe, M. Helliwell, C. A. Stevenson and T. Ladduwahetty
Tetrahedron Lett., 1998, 39, 3071-3074.
DOI:
10.1016/S0040-4039(98)00361-X
19 Applications of Stoichiometric Organotransition Metal Complexes in Organic Synthesis
Timothy J. Donohoe, Rakesh R. Harji, Peter R. Moore and Michael J. Waring
J. Chem. Soc. Perkin Transactions 1, 1998, 819-859. (Review)
DOI:
10.1039/A706382B
18 The Reduction of Electron-Deficient Pyrroles Using Group I and II Metals in Ammonia
Timothy J. Donohoe, P. M. Guyo, R. L. Beddoes and M. Helliwell
J. Chem. Soc. Perkin Transactions 1, 1998, 667-672.
DOI:
10.1039/A707661D
17 The Directed Dihydroxylation of Allylic Alcohols
Timothy J. Donohoe, Peter R. Moore, Michael J. Waring and Nicholas J. Newcombe
Tetrahedron Lett. 1997, 38, 5027-5030.
DOI:
10.1016/S0040-4039(97)01061-7
16 Applications of Stoichiometric Organotransition Metal Complexes in Organic Synthesis
Timothy J. Donohoe, Paul M. Guyo, Peter R. Moore and Clare A. Stevenson
Cont. Org. Syn. 1997, 4, 22-39. (Review)
DOI:
10.1039/CO9970400022
15 Studies on the Role of Conformation and of Hydrogen-Bonding on the Dihydroxylation of Cyclic Allylic Alcohols: Application to the Synthesis of Conduritol D
Timothy J. Donohoe, Peter R. Moore and Roy L. Beddoes
J. Chem. Soc. Perkin Transactions 1, 1997, 43-51.
DOI:
10.1039/A604052G
14 Birch Reduction of Electron-Deficient Pyrroles
Timothy J. Donohoe and Paul M. Guyo
J. Org. Chem. 1996, 61, 7664-7665.
DOI:
10.1021/jo961688u
13 On the Dihydroxylation of Cyclic Allylic Alcohols
Timothy J. Donohoe, Rina Garg and Peter R. Moore
Tetrahedron Lett. 1996, 37, 3407-3410.
DOI:
10.1016/0040-4039(96)00558-8
12 Prospects for Stereocontrol in the Reduction of Aromatic Compounds
Timothy J. Donohoe, Rina Garg and Clare A. Stevenson
Tetrahedron: Asymmetry, 1996, 7, 317-344. (Review)
DOI:
10.1016/0957-4166(96)00001-8
11 Stoichiometric Organotransition Metals in Organic Synthesis
Timothy J. Donohoe
Cont. Org. Syn. 1996, 3, 1-18. (Review)
DOI:
10.1039/CO9960300001
10 Taxane Diterpenes 3: Formation of the Eight-Membered B-Ring by Semi-Pinacol Rearrangement
Philip Magnus, Louis Diorazio, Timothy J. Donohoe, Melvyn Giles, Philip Pye, James Tarrant and Stephen Thom
Tetrahedron, 1996, 52, 14147-14176.
DOI:
10.1016/0040-4020(96)00865-4
9 Taxane Diterpenes 2: Synthesis of the 7-Deoxy ABC Taxane Skeleton, and Reactions of the A-Ring
Philip Magnus, John Booth, Louis Diorazio, Timothy J. Donohoe, Vince Lynch, Nicholas Magnus, José Mendoza, Philip Pye and James G. Tarrant
Tetrahedron, 1996, 52, 14103-14146.
DOI:
10.1016/0040-4020(96)00866-6
8 Taxane Diterpenes 1: Control of Relative and Absolute Stereochemistry in Intramolecular Pyrylium Ylide-Alkene Cyclizations for the Synthesis of Taxol Precursors
William E. Bauta, John Booth, Mary E. Bos, Mark DeLuca, Louis Diorazio, Timothy J. Donohoe, Christopher Frost, Nicholas Magnus, Philip Magnus, José Mendoza, Philip Pye, James G. Tarrant, Stephen Thom and Feroze Ujjainwalla
Tetrahedron, 1996, 52, 14081-14102.
DOI:
10.1016/0040-4020(96)00867-8
7 New Strategy for the Synthesis of the Taxane Diterpenes: Formation of the Eight-membered B-ring of Taxol by Semi-pinacol Rearrangement
P. Magnus, L. Diorazio, T. J. Donohoe, M. Giles, P. Pye, J. Tarrant and S. Thom
J. Chem. Soc., Chem. Commun. 1995, 1935-1936.
DOI:
10.1039/C39950001935
6 New strategy for the synthesis of the taxane diterpenes: Formation of the BC-rings of taxol via a [5+2]-pyrylium ylide-alkene cyclization, ring expansion strategy
W. Bauta, J. Booth, M. Bos, M. DeLuca, L. Diorazio, T. J. Donohoe, N. Magnus, P. Magnus, J. Mendoza, P. Pye, J. Tarrant, S. Thom and F. Ujjainwalla
Tetrahedron Lett. 1995, 36, 5327-5330.
DOI:
10.1016/0040-4039(95)01083-T
5 Arene Chromium Tricarbonyl Stabilised Benzylic Carbocations
Stephen G. Davies and Timothy J. Donohoe
Synlett, 1993, 323-332.
DOI:
10.1055/s-1993-22443
4 Asymmetric Synthesis via Homochiral o-Anisaldehyde Chromium Tricarbonyl
Stephen G. Davies and Timothy J. Donohoe, H. Werner, A. G. Griesbeck, W. Adam, G. Bringmann, and W. Kiefer (Eds)
Selective Reactions of Metal-Activated Molecules,
Vieweg, Braunschweig, 1992, 9-17. (Review)
DOI:
10.1016/S0957-4166(00)82002-9
3 Stereoselective Manipulation of Acetals Derived from o-Substituted Benzaldehyde Chromium Tricarbonyl Complexes
Stephen G. Davies, Timothy J. Donohoe and J. M. J. Williams
Pure and Appl. Chem. 1992, 64, 379-386. (Review)
DOI: 10.1351/pac199264030379
2 Asymmetric Synthesis of 2-Aryl-Tetrahydropyrans via Arene Chromium Tricarbonyl Methodology 2: 2-Aryl-3-Ethyl-4-Chloro-Tetrahydropyran
Stephen. G. Davies, Timothy J. Donohoe and M. Anne Lister
Tetrahedron: Asymmetry, 1991, 2, 1089-1092
DOI: 10.1016/S0957-4166(00)82003-0
1 Asymmetric Synthesis of 2-Aryl-Tetrahydropyrans via Arene Chromium Tricarbonyl Methodology 1: cis-2-Aryl-4-Chloro-Tetrahydropyrans
Stephen G. Davies, Timothy J. Donohoe and M. Anne Lister
Tetrahedron: Asymmetry, 1991, 2, 1085-1088.
DOI: 10.1016/S0957-4166(00)82002-9